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醫(yī)學(xué)論文范文:徐州礦區(qū)亞臨床甲狀腺疾病的流行特征及分析
【摘要】 目的 了解徐州礦區(qū)人群亞臨床甲狀腺疾病的患病率及流行特征。方法 應(yīng)用分層隨機(jī)整群抽樣方法調(diào)查徐州礦區(qū)常住(>5年)成年居民共468人，采用問(wèn)卷調(diào)查、體格檢查、甲狀腺B超檢查和功能檢測(cè)方法采集數(shù)據(jù)。結(jié)果 樣本總?cè)巳�、男性及女性亞臨床甲狀腺疾病的粗患病率分別為52.14%、37.01%和57.77%，甲狀腺結(jié)節(jié)、亞臨床甲狀腺功能亢進(jìn)癥和亞臨床甲狀腺功能減退癥的粗患病率分別為25.00%、4.06%和23.08%，亞臨床甲狀腺疾病的患病率隨年齡的增加呈現(xiàn)上升趨勢(shì)。女性甲狀腺結(jié)節(jié)和亞臨床甲狀腺功能減退癥患病率明顯高于男性(P<0.05)，而男性亞臨床甲狀腺功能亢進(jìn)癥患病率高于女性(P<0.01)。性別和年齡是亞臨床甲狀腺疾病發(fā)生的危險(xiǎn)因素。結(jié)論 徐州礦區(qū)成年人群亞臨床甲狀腺疾病患病率較高，應(yīng)重視對(duì)礦區(qū)人群亞臨床甲狀腺疾病的篩查、治療和隨訪。
【關(guān)鍵詞】 徐州礦區(qū);甲狀腺疾病;亞臨床;患病率
The epidemiological characteristics and analysis of subclinical thyroid diseasesin Xuzhou coal mine areas
ZHANG Shugui, JIAO Liang, GONG Ying, CAI Keying, LU Meiqi
(Department of Endocrinology, The Secend Affiliated Hospital of Xuzhou Medical College,
Xuzhou, Jiangsu 221006, China)
Abstract: Objective To explore the incidence and prevalence characteristics of subclinical thyroid diseases in Xuzhou coal mine areas. Methods 468 permanent residents from the coal mine areas of Xuzhou, who had their residence for at least five years and were aged 20 or above, were survey by stratified sampling with questionnaire, physical examination, thyroid B ultrasonic examination and functional testing in data collection. Results The prevalence of subclinical thyroid diseases in sample population, males and females was 52.14%, 37.01% and 57.77% and had a tendency of increase with age. The prevalence of thyroid nodules, subclinical hyperthyroidism and subclinical hypothyroidism was 25.00%, 4.06% and 23.08%, respectively. The prevalence of thyroid nodules and subclinical hypothyroidism was higher in females than in males (P<0.05), while males had a higher prevalence of subclinical hyperthyroidism(P<0.01). Conclusion The high prevalence of subclinical of thyroid diseases in adults in Xuzhou coal mine areas requires timely screening, treatment and follow-ups醫(yī)學(xué) 全在.線提供gydjdsj.org.cn.
Key words: Xuzhou coal mine area; thyroid diseases; subclinical; prevalence
亞臨床甲狀腺疾病是指無(wú)或僅有輕微甲狀腺疾病相關(guān)癥狀，通過(guò)實(shí)驗(yàn)室檢查或影像學(xué)手段發(fā)現(xiàn)的甲狀腺異常，包括甲狀腺結(jié)節(jié)、亞臨床甲狀腺功能亢進(jìn)和亞臨床甲狀腺功能減退等[1]。隨著診斷技術(shù)的不斷發(fā)展，亞臨床甲狀腺疾病的早期檢出率也越來(lái)越高。國(guó)內(nèi)已經(jīng)開(kāi)展多項(xiàng)關(guān)于亞臨床甲狀腺疾病的流行病學(xué)研究，而針對(duì)礦區(qū)等特殊區(qū)域人群的相關(guān)流行病學(xué)研究仍未得到重視。本研究對(duì)徐州地區(qū)的旗山礦、張雙樓礦、三河尖礦及臥牛山礦人群進(jìn)行流行病學(xué)調(diào)查，從而為徐州礦區(qū)進(jìn)行亞臨床甲狀腺疾病的防治提供基礎(chǔ)依據(jù)。
