3、原文:
Research on The Acute Toxicity of Huning CapsuleXIN Zhi-wei' ZANG Zhi-he' MAI Xiao-xia' FENG Jun' YANG Wan-qing' LIAO Hong-li (Teaching and Research Section of Pharmacy' The Third Medical University' Chengdu College of PLA 610081' China)ABSTRACT Objective: To observe and test the acute toxicity of Huning Capsule on Kunming mice after an i.g. Methods: Count the death cases of mice in 7 days after the i.g. and work out the LD50 of Huning Capsule. Results: The LD50 of Huning Capsule on mice is 3981mg/kg.KEY WORDS Huning Capsule; Acute Toxicity; LD50修正:An Experimental Study of the Acute Toxicity of Huning Capsules1XIN Zhi-wei' ZANG Zhi-he' MAI Xiao-xia' FENG Jun' YANG Wan-qing' LIAO Hong-li (Teaching and Research Section of Pharmacy' Chengdu Military Medical College' The Third Military Medical University' Chengdu 610081' China)ABSTRACT Objective: To observe and determine the acute toxicity of Huning capsules (on Kunming mice刪去) after a single
intragastric administration in the mouse. Methods: 50 Kunming mice were randomly divided into
5 equal groups' with 10 animals in each group. A single dose of 7500' 5630' 4200' 3150 and 2360mg/kg-1 of the content of the capsules were administened through a gastric tube to each of the mice of the 5 groups' respectively. The numbers of the deaths of the mice within 7 days were noted down and the mediar lether dose (LD50) of Huning Capsules was calculated. (Count the death cases of mice in 7 days after the i.g. and work out the LD50 of Huning Capsule. 刪去) Results: The LD50 of Huning Capsule in mice was 3981mg/kg. Conclusion: Huning Capsules have only a minor acute toxicity. It is therefore safe to use the drug clinically. Further study of its toxicity in long-term application is required.KEY WORDS Huning Capsules; Toxicity' acute; LD50
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1、“呼寧膠囊”也可譯作antitussive and antiasthmatic capsules.