美登普林

結(jié)晶(二氯乙烷-乙醚),熔點(diǎn)178°,[α]23/D-126.9°(C=0.026,氯仿)。UV λEtOHmax nm(ε):233(32780),242(30320),254(29610),282(5110),290(4970)。IR λKBrmax cm\-1:1739,1724,1661,1577,1188,1080。MSm/e:705(M+),644,485,470,450,142,114,58,44。NMR(CDCl3)δ:0.87(3H,s,C-4CH3),1.18(3H,t,J=7,C-4'CH3),1.35(3H,d,J=7,C-6CH3),1.36(3H,d,J=7,C-2'CH3),1.70(3H,br.s,C-14CH3),2.19(1H,dd,J2,2=14,J2,3=3,C-2H),2.37(1H,m,C-4'H),2.41(1H,m,C-4'H),2.64(1H,dd,J2,2=14,J2,3=12,C-2H),2.86(3H,s,C-2'NCH3),3.04(1H,d,J5,6=9,C-5H),3.12(1H,d,J15,15=12,C-15H),3.21(3H,s,C-1NCH3),3.38(3H,s,C-10OCH3),3.50(1H,d,J10,11=9,C-10H),3.55(1H,s,C-9OH),3.68(1H,d,J15,15=12,C-15H),4.00(3H,s,C-20OCH3),4.28(1H,m,C-7H),4.79(1H,dd,J2,3=12,2.5,C-3H),5.40(1H,q,J=7,C-2'H),5.67(1H,dd,J=10,11=9,J11,12=15,C-11H),6.26(1H,br.s,C-9NH),6.42(1H,dd,J11,12=15,J12,13=11,C-12H),6.67(1H,br.d,J12,13=11,C-13H),6.66,6.82(2H,d,J17,21=1.5,C-17H,C-21H),0.8～2.0(3H,C-6H,C-8H)。