田英,女,教授。上海交通大學(xué)醫(yī)學(xué)院環(huán)境衛(wèi)生學(xué)教研室主任。上海市預(yù)防醫(yī)學(xué)會(huì)衛(wèi)生毒理專業(yè)委員會(huì)委員,中華預(yù)防醫(yī)學(xué)會(huì)勞動(dòng)衛(wèi)生職業(yè)病分會(huì)婦女勞動(dòng)衛(wèi)生學(xué)組委員。1990年7月畢業(yè)于中國(guó)醫(yī)科大學(xué)環(huán)境衛(wèi)生學(xué)專業(yè),獲醫(yī)學(xué)碩士學(xué)位。1996-2003年在日本的國(guó)立日本三重大學(xué)醫(yī)學(xué)部公共衛(wèi)生學(xué)教研室學(xué)習(xí)和工作。參與和主持完成三項(xiàng)日本國(guó)家級(jí)、省部級(jí)課題,在外來(lái)化合物尤其是有機(jī)磷農(nóng)藥致后代健康影響評(píng)價(jià)方面,生殖毒性、免疫毒性、神經(jīng)毒性遲發(fā)性反應(yīng)機(jī)理等方面做了大量的研究工作,取得了豐碩的研究成果。近5年來(lái),在上述研究領(lǐng)域,用英、日、中文在國(guó)際重要學(xué)術(shù)期刊發(fā)表論文20余篇,其中SCI論文10篇,影響因子合計(jì)15.5分。2003年作為重點(diǎn)學(xué)科建設(shè)人才引進(jìn)到上海第二醫(yī)科大學(xué)公共衛(wèi)生學(xué)院工作,發(fā)表SCI論文5篇,并獲得國(guó)家自然科學(xué)基金、國(guó)家教育部等多項(xiàng)科研課題。
研究方向: 環(huán)境污染與生殖健康。
環(huán)境外來(lái)化合物對(duì)生殖、胚胎發(fā)育影響。重點(diǎn)研究低劑量慢性暴露生殖發(fā)育毒性,暴露與早期效應(yīng)的生物標(biāo)志物,環(huán)境外來(lái)化合物的基因毒理學(xué)等。評(píng)價(jià)環(huán)境外來(lái)化合物慢性暴露的危險(xiǎn)性,為育齡婦女長(zhǎng)期接觸體內(nèi)安全劑量的設(shè)定、采取相應(yīng)的預(yù)防措施提供最有價(jià)值的科學(xué)依據(jù)。
在研課題: 共4項(xiàng),總經(jīng)費(fèi) 40萬(wàn)。
其中,05年獲國(guó)家自然科學(xué)基金項(xiàng)目一項(xiàng)(30571542;2006-2008);國(guó)家教育部項(xiàng)目一項(xiàng)(05-55-1;2005-2007),上海市人事局項(xiàng)目、上海第二醫(yī)科大學(xué)項(xiàng)目各一項(xiàng)。
研究成果:
1. Y. Tian, T. Yamauchi,I. Hitoshi, T Yamaguchi , Toru Yamauchi , Kazuhito Yokoyama. Teratogenicity and developmental toxicity of chlorpyrifos: Maternal exposure during organogenesis in mice. Reproduction Toxicology 2005, 20:267-271
2. H. Ishikawa, H. Yamamoto, Y. Tian, M. Kawano, T. Yamauchi, K.Yokoyama. Evidence of association of the CYP2E1 genetic polymorphism with micronuclei frequency in human peripheral blood. Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis 2004, 546: 45-53
3. Y. Tian, H. Ishikawa, T. Yamauchi. Analysis of cytogenetic and developmental effects on pre-implantation mouse embryos after maternal treatment with organophosphate insecticide. Journal of Environmental and Occupational Medicine 2004, 21(5): 391-393醫(yī)學(xué) 全在.線提供www.med126.com
4. Y. Tian, T. Yamauchi. Micronucleus formation in 3-day mouse embryos associated with maternal exposure to chlorpyrifos during early preimplantation period Reproduction Toxicology 2003, 17: 401-405
5. Y. Tian.,H. Ishikawa, F. Piao , H. Yamamoto, T. Yamauchi,Zh. Duan,Y. Zhang, M. Ma, J. Cui. Micronucleus assay of human lymphocytes: a comparison of cytokinesis-block and human capillary blood lymphocytes methods. Journal of Occupational Health 2003, 45: 408-409
6. H. Ishikawa, Y. Tian, and T. Yamauchi. Influence of gender, age and lifestyle factors on micronuclei frequency in healthy Japanese populations. Journal of Occupational Health 2003, 45:179-181
7. H. Ishikawa, H. Yamamoto, Y. Tian.,M. Kawano, T. Yamauchi, K. Yokoyama. Effects of ALDH2 genepolymorphisms and alcohol-drinking behavior on micronuclei frequency in non-smokers. Mutation Research 2003, 541: 71-80
8. 田英、石川仁、樸豊源、山內(nèi)徹. 有機(jī)燐殺蟲剤の著床前マウス胎児に及ぼす影響の検討日本衛(wèi)生學(xué)會(huì)雑誌.2002, 57(1):222
9. H. Ishikawa, Y. Tian, T. Yamauchi. Induction of micronuclei formation in preimplantation mouse embryos after maternal treatment with 2- bromopropane. Reproduction Toxicology 2001,15: 81-85
10. 田英、石川仁、樸豊源、山內(nèi)徹. 有機(jī)燐殺蟲剤Trichlorfonのマウス胎児発育に及ぼす影響 日本衛(wèi)生學(xué)會(huì)雑誌 2001, 56(1): 267
11. Y. Tian, H. Ishikawa, T. Yamauchi. Analysis of cytogenetic and developmental effects on pre-implantation, midgestation, and near-term mouse embryos after treatment with trichlorfon during zygote stage. Mutation Research 2000, 471: 37-44
招生要求:有志于環(huán)境與健康方面研究的醫(yī)學(xué)生。