醫(yī)學(xué)論文范文:三維適形放療同步TP方案化療治療局部晚期非小細(xì)胞肺癌

本研究結(jié)果顯示,兩組患者的總有效率分別為56.7%和81.8%,其中CR率分別為6.7%和27.3%,顯示三維適形放療聯(lián)合多西他賽近期療效明顯優(yōu)于序貫放化療。兩組1、2年生存率分別63.5% (19/30)、79.4% (26/33)和40.0%(12/30)、54.4% (18/33),三維適形放療聯(lián)合多西他賽組比序貫放化療組高出十多個(gè)百分點(diǎn),中位生存期亦比其高出7.5個(gè)月,雖無統(tǒng)計(jì)學(xué)意義,仍顯示提高局部控制可使患者的長期生存獲益。研究結(jié)果因觀察時(shí)間有限,遠(yuǎn)期療效和并發(fā)癥有待進(jìn)一步隨訪。

綜上所述, TP方案聯(lián)合三維適形放療治療晚期非小細(xì)胞肺癌有比較好的療效及安全性,可延長生存期,急性毒副反應(yīng)可耐受。因此TP方案聯(lián)合放療治療晚期非小細(xì)胞肺癌是一種積極有效的措施。

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