（一)發(fā)表相關(guān)論文目錄 (英文)：
• *Jinbao Liu , Mingxin Tang, Ruben Mestril, Xuejun Wang. Aberrant protein aggregation is essential for a mutant desmin to impair the proteolytic function of the ubiquitin-proteasome system in cardiomyocytes. J Mol Cell Cardiol . 2006 Feb 13; [Epub ahead of print] PMID: 16481005
• *Jinbao Liu , Quanhai Chen, Wei Huang, Kathleen M. Horak, Hanqiao Zheng, Ruben Mestril and Xuejun Wang. gydjdsj.org.cn Impairment of the ubiquitin-proteasome system in desminopathy mouse hearts. FASEB J . 2006 Feb;20(2):362-4. Epub 2005 Dec 21.
• *Quanhai Chen* , Jinbao Liu* , Hathleen M. Horak, Hanqiao Zheng, Asangi R.K. Kumarapeli, Jie Li, Faqian Li, A. Martin Gerdes, Eric F. Wawrousek and Xuejun Wang. Intrasarcoplasmic amylodosis impairs proteolytic function of proteasomes in cardiomyocytes by compromising substrate uptake Circ Res 2005; 97: 1018-1026 ( *equal contribution )
• Asangi R. K. Kumarapeli, Kathleen M. Horak, Joseph W. Glasford, Jie Li, Quanhai Chen, Jinbao Liu, Hanqiao Zheng, and Xuejun Wang . A novel transgenic mouse model reveals deregulation of the ubiquitin-proteasome system in the heart by doxorubicin FASEB J . 2005; 19: 2051-2053.
• *Xin Dong*, Jinbao Liu*, Hanqiao Zheng, Joseph W. Glassford, Wei Huang, Quanhai Chen, Niels R. Harden, Faqian Li, A. Martin Gerdes and Xuejun Wang. In situ dynamically monitoring the proteolytic function of the ubiquitin-proteasome sytem in cultured cardiac myocytes Am J Physiol-Heart Circ Physiol 2004;287:H1417-H1425 (*equal contribution)
（二)發(fā)表摘要及國(guó)際會(huì)議報(bào)告目錄（英文)
• Chen Q, Liu J , Horak KM, Zheng H, Li J, Tang M, Su H, Kumarapeli AR, Li F, Gerdes AM, Wang X. Cytoplasmic aberrant protein aggregation impairs protein degradation in the heart by compromising the entry of ubiquitinated proteins into the 20S proteasomes. Circulation 2005 Oct 25; 112(17): II-188. AHA Scientific Sessions, November 12-16, 2005, Dallas, TX.
• Liu J , Chen Q, Wang X. Aberrant protein aggregation impairs protein degradation in mouse heart. AHA Research Symposium, November 12, 2005, Dallas, TX.
• Liu J , Chen Q, Huang W, Horak K, Zheng H, Mestril R, Wang X. Aberrant protein aggregation impairs the ubiquitin-proteasome system by affecting the entry of ubiquitinated proteins into the 20S proteasomes: A novel pathogeneic pathway in cardiac remodeling and failure. Second Annual Symposium of the AHA Council on Basic Cardiovascular Sciences. July 24-27, 2005, Keystone, CO.
• Liu J , Tang M, Chen Q, Wang X. H2O2 inhibits proteolytic function of the ubiquitin-proteasome system by gydjdsj.org.cn activating caspases. Experimental Biology/IUPS 2005 Late Breaking Abstracts, LB15. San Diego, CA, March 31-April 5, 2005.
• Wang X, Chen Q, Liu J , Kumarapeli ARK, Zheng H, Horak K, Glasford JW, Gerdes AM, Li F. A novel functional indicator mouse model reveals impairment of the ubiquitin-proteasome system by misfolded proteins in the heart. The Inaugural Annual Symposium on Protein Folding Disorders. San Diego, CA, Jan 11-13, 2005.
• Wang X, Liu J , Chen QH, Dong X, Wawrousek EF, Li F, Horak K. Impairment of the ubiquitin-proteasome system by misfolded cytoplasmic protein in cardiac myocytes. Circulation 2004; 110 (17):III-160. Oral presentation at AHA Scientific Sessions 2004, New Orleans, LA, November 7-10, 2004.
• Kumarapeli AR, Liu J , Glasford JW, Chen QH, Horak K, Dong X, Wang X. Myocardial ischemia/reperfusion impairs the ubiquitin-proteasome system: role of reactive oxygen species. Circulation 2004; 110(17): III-237. Oral presentation at AHA Scientific Sessions 2004, New Orleans, LA, November 7-10, 2004.
• Liu J , Chen QH, Wang X. Impairment of the ubiquitin-proteasome system in cardiac myocytes by reactive oxygen species revealed by a surrogate substrate. Circ Res 2004, 94(12):data supplement on abstracts of 1 st Annual Symposium of the AHA Council on Basic Cardiovascular Sciences. July 14-18, 2004, Stevenson, WA.
• Wang X, Kumarapeli AR, Glasford J, Liu J , Chen QH, Horak K, Zheng H, Dong X. In vivo monitoring dynamic changes in the proteolytic function of the ubiquitin-proteasome system. (A late-breaking abstract presented in 1 st Annual Symposium of the AHA Council on Basic Cardiovascular Sciences. July 14-18, 2004, Stevenson, WA.)
