姓名: | 潘建平 |
職務(wù): | PI |
職稱(chēng): | 教授 |
學(xué)歷: | 博士研究生 |
專(zhuān)業(yè): | 免疫學(xué)/病原生物學(xué) |
所屬院系: | 基礎(chǔ)醫(yī)學(xué)系 |
研究方向: | 感染免疫學(xué) |
電話: | 0571-88206896 |
信箱: | jppan@zju.edu.cn |
個(gè)人簡(jiǎn)介
浙江大學(xué)醫(yī)學(xué)部病原生物學(xué)系副主任、免疫學(xué)教授、博士研究生導(dǎo)師,中國(guó)免疫學(xué)會(huì)理事,浙江省免疫學(xué)會(huì)感染免疫專(zhuān)業(yè)委員會(huì)主任委員gydjdsj.org.cn,浙江省抗癌協(xié)會(huì)腫瘤生物治療委員會(huì)委員兼秘書(shū),“International Journal of Cancer”、“Vaccine”等期刊審稿人。
主要研究方向:腫瘤免疫學(xué),黏膜抗感染免疫的細(xì)胞和分子機(jī)制
在研科主要研項(xiàng)目:不同亞群PP-DC在B細(xì)胞向腸黏膜歸巢和IgA產(chǎn)生中的作用及其機(jī)制(國(guó)家自然科學(xué)基金,30872325)
發(fā)表的主要論文:
1.Lu J, Zheng MH, Yan J, Chen YP, Pan J. Effects of vasoactive intestinal peptide on phenotypic and functional maturation of dendritic cells. Inter Immunopharmacol 2008; 8:1449-1454.
2.Pan J, Jin P, Yan J, Kabelitz D. Anti-angiogenic active immunotherapy: a new approach to cancer treatment. Cancer Immunol Immunother 2008; 57:1105-1114.
3.Weng Y, Sun J, Wu Q, Pan J. Regulatory effects of vasoactive intestinal peptide on the migration of mature dendritic cells. J Neuroimmunol 2007; 182: 48-54.
4.Shao P, Zhao LH, Chen Z, Pan J. Regulation on maturation and function of dendritic cells by Astragalus mongholicus polysaccharides. Inter Immunopharmacol 2006; 6: 1161-1166.gydjdsj.org.cn
5.Pan J, Heiser A, Maret M, Steinmann J, Kabelitz D. Enhanced anti-metastatic effect of fetal liver kinase 1 and interferon-gamma fusion gene-modified dendritic cell vaccination. Gene Ther 2005; 12:742-750.
6.Pan J, Zhang M, Wang J, Wang Q, Xia D, Sun W, Zhang L, Yu H, Cao X. Intratumoral injection of interferon-gamma gene-modified dendritic cells elicits potent antitumor effects: effective induction of tumor-specific CD8+ CTL response. J Cancer Res Clin Oncol 2005; 131:468-478.
7.Pan J, Zhang M, Wang J, Wang Q, Xia D, Sun W, Zhang L, Yu H, Liu Y, Cao X. Interferon-gamma is an autocrine mediator for dendritic cell maturation. Immunol Lett. 2004; 94 : 141-151.
8.Pan J, Ju DW, Wang Q, Zhang M, Xia D, Zhang L, Yu H, Cao X. Dexamethosone inhibits the antigen presentation of dendritic cells in MHC class II pathway. Immunol Lett 2001; 76 (3): 153-161.
9.Zhang LH,Pan JP,Yao HP, et al. Intrasplenic transplantation of IL-18 gene-modified hepatocytes: an effective approach to reverse hepatic fibrosis in schistosomiasis through induction of dominant Th1 response. Gene Ther 2001; 8: 1333-1342.