特色：胰腺疾病的、手段和意義，實(shí)驗(yàn)/臨床工作條件 主要研究成果： 主要論著 1.Lu Xia,Yaozong Yuan, Chundi Xu, et al.Effects of epidermal growth factor on the growth of human gastric cancer cell and the implanted tumor of nude mice. World J Gastroenterol 2002; 8(3):455 2.Lu Xia, Ying Bao, Yaozong Yuan, et al.All-trans retinoid acid-induced apoptosis in pancreatic cancer cells is mediated by bcl-2/bax and p53 expression. （2003年美國消化病周學(xué)術(shù)大會(huì)） 3.夏璐, 鮑英,袁耀宗, 等.全反式維甲酸和Caspase抑制劑Z-VAD-FMK對(duì)胰腺癌細(xì)胞凋亡的作用.胰腺病學(xué)，2003,3(4):198 4.夏璐, 袁耀宗.Bcl-2家族對(duì)細(xì)胞凋亡的作用及其在胰腺癌中的表達(dá).國外醫(yī)學(xué)消化分冊(cè),2003;23(4):152（綜述） 5.夏璐, 鮑英,袁耀宗, 等.全反式維甲酸誘導(dǎo)胰腺癌細(xì)胞凋亡機(jī)制研究. 中華消化雜志 2004.7（24）：391 6.鮑英,夏璐,袁耀宗, 等.康萊特對(duì)人胰腺癌細(xì)胞凋亡的實(shí)驗(yàn)研究.上海醫(yī)學(xué) 2004;27(6):421 7.Lu Xia, Qihuang Jin, Yaozong Yuan, et al. Human acetylcholinesterase gene transfer in pancreatic cancer cells enhance the effect of all-trans retinoic acid induced apoptosis. J Gastroenterol Hepatol，2004，19（Suppl）：A580(論文摘要) 8.Lu Xia, Ying Bao, Yaozong Yuan, et al. Immunohistochemical study of p53 , caspase-7 and bcl-2/bax in pancreatic cancer and chronic pancreatitis. Pancreas 2003；27（4）：426 9.Ying Bao ，Lu Xia, Yaozong Yuan, et al. Kanglaite, an acetone extract of the Coix Seed, inhibits proliferation of human pancreatic cancer cells via cell cycle arrest and apoptosis. Pancreas 2003；27（4）：424 10.Ying Bao, Yaozong Yuan, Lu Xia, et al.Neutral lipid isolated from endosperm of Job##s tears inhibits the growth of pancreatic cancer cells via apoptosis,G2/M arrest, and regulation of gene expression. J Gastroenterol and Hepatol 2005;20:1046-1053 11.沈俊，夏璐, 諸琦，等.芍藥甙對(duì)犬急性重癥胰腺炎奧狄括約肌功能的影響. 中國中西醫(yī)結(jié)合消化雜志，2004，12（2）：77 12.Lu Xia, Ying Bao, Yaozong Yuan, et al.The Effect of Histone H3 Acetylation on the Cell Cycle Arrest Induced by All-trans Retinoic Acid in Pancreatic Cancer Cells. J Gastroenterol Hepatol，2004，19（Suppl）：A583 13.Lu Xia, Ying Bao, Yaozong Yuan, et al.All-trans retinoic acid induce alteration of specific chromatin acetylation via inhibition of histone deacetylase in pancreatic cancer cells.J Gastroenterol and Hepatol，2004，19（Suppl）：A580 14.Lu Xia, Jihong Tan, Qi Zhu, et al.Value of miniprobe sonography in the evaluation of remission of ulcerative colitis. J Gastroenterol Hepatol，2004，19（Suppl）：A659 15.夏璐, 金其煌,袁耀宗,等.人乙酰膽堿酯酶基因轉(zhuǎn)染增強(qiáng)全反式維甲酸誘導(dǎo)胰腺癌細(xì)胞凋亡. 中華消化雜志2005，25（5）：77 16.Y.Bao,Y.Yuan,L Xia. Neutral lipid isolated from endosperm of Job##s tears inhibits the growth of pancreatic cancer cells via apoptosis,G2/M arrest and regulation of gene expression.J Gastroenterol Hepato 2005,20:1046 17.L. Li, Y. Yuan, J. Lu, L. Xia. Treatment of pancreatic carcinoma by adenoviral mediated gene transfer of vasostatin in mice. Gut 2005,55: 259 主要參編著作 1.消化系統(tǒng)常見急診：現(xiàn)代急診內(nèi)科學(xué). 科學(xué)出版社. 2004 2.慢性胰腺炎發(fā)病機(jī)制與臨床診治：消化系疾病臨床新技術(shù).人民軍醫(yī)出版社. 2002 3.超聲大腸鏡：下消化道內(nèi)鏡學(xué). 上�？茖W(xué)技術(shù)出版社. 2003 4.胰腺外分泌功能檢查：中華內(nèi)科學(xué). 2004 5.急性胰腺炎、慢性胰腺炎："面向21世紀(jì)"內(nèi)科學(xué).人民衛(wèi)生出版社. 2001 6.食道正常功能和疾�。晝�(nèi)鏡：舒斯特胃腸動(dòng)力學(xué)（第二版）上�？茖W(xué)文獻(xiàn)出版社.2003
獲獎(jiǎng)情況 1.全反式維甲酸誘導(dǎo)胰腺癌細(xì)胞凋亡過程中p53和bcl-2/bax表達(dá)的變化2003年全國胰腺疾病大會(huì)優(yōu)秀論文一等獎(jiǎng)（第一作者） 2.Neutral lipid isolated from endosperm of Job##s tears inhibits the growth of pancreatic cancer cells via apoptosis,G2/M arrest, and regulation of gene expression.第12屆歐洲消化病周優(yōu)秀論文獎(jiǎng)(2004)（課題設(shè)計(jì)，主要參加） 3.All-trans retinoic acid induce alteration of specific chromatin acetylation via inhibition of histone deacetylase during the cell cycle arrest in pancreatic cancer cells. 2005年 APDW Travel Award（第一作者） 4.2005年上海第二醫(yī)科大學(xué)"百人計(jì)劃" 5.2005年上海市衛(wèi)生局高級(jí)西學(xué)中培養(yǎng)計(jì)劃
