|
簡(jiǎn)歷：薛曉文，博士，現(xiàn)任中國藥科大學(xué)藥物化學(xué)教研室副教授，主要從事有機(jī)化學(xué)以及藥物化學(xué)領(lǐng)域的研究。1986年畢業(yè)于原南京藥學(xué)院化學(xué)制藥專業(yè)，留校任教。2000年赴美留學(xué)，2005年獲美國邁阿密大學(xué)化學(xué)系有機(jī)化學(xué)專業(yè)博士學(xué)位。2005-2006年美國邁阿密大學(xué)化學(xué)系博士后。2006年9月回到中國藥科大學(xué)工作。美國化學(xué)會(huì)會(huì)員。在化學(xué)領(lǐng)域的權(quán)威雜志美國化學(xué)會(huì)志（The Journal of American Chemical Society）以及有機(jī)化學(xué)雜志（The Journal of Organic Chemistry）等上發(fā)表了7篇SCI論文（其中6篇的影響因子在3.0 以上）。
研究領(lǐng)域：抗腫瘤藥物研究；非共價(jià)鍵弱作用力研究；不對(duì)稱反應(yīng)起源的研究等。
主要論著：
1. Benjamin W. Gung,* Xiaowen Xue and Zou Yan, “Enthalpy (H) and Entropy (S) for ∏-Stacking Interactions in Near-Sandwich Configurations: Relative Importance of Electrostatic, Dispersive, and Charge-Transfer Effects”, J. Org. Chem. 2007, 72, 2469.
2. Benjamin W. Gung,* Mehul Patel and Xiaowen Xue, “A Threshold for Charge-Transfer Effects in Aromatic Interactions? Quantitative Study of π-Stacking Interactions ”, J. Org. Chem. 2005, 70, 10532.
3. Benjamin W. Gung,* Xiaowen Xue and Hans J. Reich, “Off Center Oxygen-Arene Interactions in Solution: A Quantitative Study”, J. Org. Chem. 2005, 70, 7232.
4. Benjamin W. Gung,* Xiaowen Xue and Hans J. Reich, “The Strength of Parallel-Displaced Arene-Arene Interactions in Chloroform”, J. Org. Chem. 2005, 70, 3641.
5. Benjamin W. Gung,* Xiaowen Xue, Nina Knatz, and James A. Marshall, “Addition of chiral allenylzinc reagent to acetaldehyde: diastereotopic cyclic transition states with a tetrahedral zinc atom located by ab initio and density functional theory”, Organometallics 2003, 22, 3158. 醫(yī)學(xué)全.在.線網(wǎng)站gydjdsj.org.cn
6. Benjamin W. Gung,* Xiaowen Xue, and William R. Roush, “The origin of diastereofacial control in allyboration reactions using tartrate ester derived allylboronates: attractive interactions between the Lewis acid coordinated aldehyde carbonyl group and an ester carbonyl oxygen”, J. Am. Chem. Soc. 2002, 124, 10692.
7. Benjamin W. Gung* and Xiaowen Xue, “Asymmetric transition states of allylation reaction: an ab initio molecular orbital study”, Tetrahedron: Asymmetry 2001, 12, 2955.
Resume
Xiaowen Xue，PhD， associate professor of Medicinal Chemistry , China Pharmaceutical University. Xiaowen Xue graduated from Nanjing College of Pharmacy with a BS in 1986 and worked as a teacher in the same college until he moved to USA to pursue his PhD in 2000. Xiaowen Xue obtained his PhD majoring at organic chemistry from Miami University in 2005, under the guidance of Prof Ben Gung. He then did his postdoctoral research at Miami for one year and returned to China Pharmaceutical University in 2006, where he holds the associate professorship. He is the member of American Chemical Society. During his American career, Xiaowen Xue coauthored seven peer-reviewed publications at top chemistry journals such as the Journal of American Chemical Society and the Journal of Organic Chemistry.
Research Interests
The research on anticancer drugs; studies on weak noncovalent interactions; and the origins of some asymmetrical reactions.
References
1. Benjamin W. Gung,* Xiaowen Xue and Zou Yan, “Enthalpy (H) and Entropy (S) for ∏-Stacking Interactions in Near-Sandwich Configurations: Relative Importance of Electrostatic, Dispersive, and Charge-Transfer Effects”, J. Org. Chem. 2007, 72, 2469.
2. Benjamin W. Gung,* Mehul Patel and Xiaowen Xue, “A Threshold for Charge-Transfer Effects in Aromatic Interactions? Quantitative Study of π-Stacking Interactions ”, J. Org. Chem. 2005, 70, 10532.
3. Benjamin W. Gung,* Xiaowen Xue and Hans J. Reich, “Off Center Oxygen-Arene Interactions in Solution: A Quantitative Study”, J. Org. Chem. 2005, 70, 7232.
4. Benjamin W. Gung,* Xiaowen Xue and Hans J. Reich, “The Strength of Parallel-Displaced Arene-Arene Interactions in Chloroform”, J. Org. Chem. 2005, 70, 3641.
5. Benjamin W. Gung,* Xiaowen Xue, Nina Knatz, and James A. Marshall, “Addition of chiral allenylzinc reagent to acetaldehyde: diastereotopic cyclic transition states with a tetrahedral zinc atom located by ab initio and density functional theory”, Organometallics 2003, 22, 3158.
6. Benjamin W. Gung,* Xiaowen Xue, and William R. Roush, “The origin of diastereofacial control in allyboration reactions using tartrate ester derived allylboronates: attractive interactions between the Lewis acid coordinated aldehyde carbonyl group and an ester carbonyl oxygen”, J. Am. Chem. Soc. 2002, 124, 10692.
7. Benjamin W. Gung* and Xiaowen Xue, “Asymmetric transition states of allylation reaction: an ab initio molecular orbital study”, Tetrahedron: Asymmetry 2001, 12, 2955
... |
