| 化學(xué)名 | 4H-1,16-Etheno-5,15-(propaniminoethano)furo[3,4-l][1,5,10]triazacyclohexadecine-4,21-dione,3,3a,6,7,8,9,10,11,12,13,14,15-dodecahydro-3-(3,4-dimethoxyphenyl)-,[3R-(3R*,3aR*,15S*)]
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| 藥物名稱 | Ephedradine C
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| 異名（中) | |
| 異名（英) | |
| 分子量 | 536.65
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| 理化性質(zhì) | 未分得游離堿結(jié)晶。二氫溴酸鹽(C30H40N4O5·2HBr·H2O)熔點(diǎn)224～225°,[α]D-100.7°(水)。13CNMR(D2O)δ:88.0(d,C-2),52.0(d,C-3),125.8(s,C-4),133.4(d,C-5),126.1(s,C-6),121.0(d,C-7),111.3(d,C-8),159.1(s,C-9),130.7(s,C-10),110.4(d,C-11),148.4(s,C-12),148.0(s,C-13),109.8(d,C-14),119.7(d,C-15),170.7(s,C-16),58.7(d,C-17),174.5(s,C-19),21.4(t,C-18),22.8(t,C-2'),25.2(t,C-13'),25.4(t,C-13'),37.7(t),37.9(t),41.9(t),42.6(t),44.2(t),46.0(t),46.0(t),55.5(q,CH30),55.5(q)。
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| 構(gòu)效關(guān)系 | |
| 藥化作用 | 大鼠靜脈注射本品二氫溴酸鹽2.0mg/kg時(shí),能引起明顯的血壓降低。
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| 毒性 | |
| 臨床 | |
| 不良反應(yīng) | |
| 成分分類 | |
| 用途分類 | |
| 來源 | 麻黃科麻黃屬 Ephedra 植物的根。
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| 化學(xué)號(hào) | |
| 參考文獻(xiàn) | 1.《植物藥有效成分手冊(cè)》人民衛(wèi)生出版社1986
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| 分子式 | C30H40N4O5
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| 熔點(diǎn) | |
| 旋光度 | |
| 沸點(diǎn) | |
| 來源拉丁學(xué)名 |
